Known as an aromatase inhibitor (AI) (source), the drug Arimidex blocks the aromatase enzyme and prevents it from producing estrogen in the body. Arimidex is used clinically in women who are suffering from breast cancer. It is administered to them to halt the progression of the cancerous cells. However, bodybuilders and athletes include Arimidex in their anabolic steroid cycles as it is known to increase testosterone levels slightly as well as having estrogen-reducing properties.
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Anyone using anabolic steroids will suffer from a number of unwanted side effects. These include acne, gynecomastia, water retention, and other symptoms. These side-effects are caused by the anabolic steroids converting to estrogen by way of the aromatase enzyme, the process is known as ‘aromatizing’. Studies have shown that 5mg and 1mg doses of Arimidex decrease this process by around 50%. A 1mg dose of Arimidex increased testosterone levels by 58%. These studies, and in particular one of them, showed both groups LH and FSH increased marginally as well.
In the average young man aged 15 – 22, testosterone and E2 concentrations were also seen to change before and after a 10-day oral course of anastrozole at a dosage of 0.5 and 1mg. The results of these studies do suggest that one single dose of .5mg would combat the side effects that are associated with estrogen. One factor that has to be taken into consideration is that to obtain optimal muscle growth, the body does require some estrogen in order to do this. To achieve ‘harder’ and therefore a better ‘quality’ appearance during cutting cycles, body-builders, anecdotally at least, would need lower estrogen levels.
With the increase in levels of testosterone being so high, it is at this point that it needs to be pointed out that Arimidex can be used as a testosterone replacement therapy for men who are suffering from a condition known as Hypogonadism. This is a medical term that describes a lowered function of the gonads which results in less testosterone being produced. The end result of the use of Arimidex in these instances would mean that PCT (post-cycle therapy) would be enhanced and therefore natural testosterone levels would be regained as well as the Hypothalamic-Testicular-Pituitary-Axis, HTPA functioning as it should.
The original manufacturer of Anastrozole – Arimidex is produced by Zeneca Pharmaceuticals – provides users with a pamphlet that indicates that after only 7 consecutive daily doses of 1mg will produce stable blood plasma concentrations. As well as this Arimidex as an aromatase inhibitor is 80% effective. This means that anyone who starts taking the compound a week before cycling will benefit from the full effects of using Arimidex.
However, it is possible to take it for the duration of the cycle, but is this safe to do? From a bodybuilding point of view, lower estrogen levels are a bonus, water retention is reduced as well as any potential for gynecomastia. One factor in favor of using Arimidex is that it is gentle on blood lipids also known as cholesterol and studies have shown that it does not appear to affect them in any adverse manner.
However, as previously stated, lowered estrogen levels may affect cholesterol levels and possibly have adverse immune system effects. For short-term use when taken during an entire cycle and PCT, Arimidex can be used and some experts recommend this. For anyone on long and heavy cycles, then this should be taken as an ancillary compound. This is especially true as Arimidex does not prevent or inhibit the Insulin-like growth factor, IGF which other ancillary compounds tend to do.
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- When should I take anastrozole during steroid cycle?
Anastrozole is commonly prescribed during a steroid cycle to protect against estrogen-related side effects like gynecomastia. Typically, it's taken every other day starting at the start of the cycle or when symptoms of high estrogen appear. However, dosage and frequency may differ depending on which steroids are taken and individual responses to treatment. It's best to consult with a healthcare professional for precise dosing instructions and timing before beginning anastrozole during your steroid cycle.
- Should I take Arimidex during my cycle?
Arimidex (anastrozole) during a steroid cycle depends on several factors, including the type and dose of steroids used, individual susceptibility to estrogen-related side effects, and what goals the cycle is intended for. Arimidex is often prescribed to inhibit testosterone conversion into estrogen and reduce the likelihood of side effects like gynecomastia, water retention or high blood pressure. However, excessive suppression of estrogen may lead to negative consequences like decreased libido, joint pain or an increased risk for cardiovascular disease – so use Arimidex with caution under medical guidance.
- Can you take Arimidex while on testosterone?
Yes, Arimidex (anastrozole) can be taken while on testosterone to help manage estrogen levels. It's often prescribed by bodybuilders and athletes using testosterone or other aromatizable steroids in order to prevent or reduce the risk of estrogen-related side effects like gynecomastia, water retention, and high blood pressure. However, it's essential that you follow the doctor's instructions closely and regularly monitor hormone levels in order to avoid negative impacts on mood, libido, or bone health.
- How much Arimidex should I take while taking testosterone?
When taking Arimidex (anastrozole), the appropriate dosage depends on individual circumstances. It's best to consult a healthcare provider or experienced steroid cycle coach for guidance in determining your individual dosage. Generally, Arimidex dosages range from 0.25 mg per day up to 1 mg daily. To prevent unwanted side effects, monitor estradiol levels regularly and adjust dosage accordingly.
- When is the best time to take Arimidex?
Arimidex (anastrozole) is often prescribed by bodybuilders in order to protect them from estrogen-related side effects when taking anabolic steroids. The dosage and timing of Arimidex depend on several factors, including the type and dose of steroids being taken as well as individual response and tolerance to the drug.
As a general guideline, Arimidex should be taken every other or third day during the initial week of a steroid cycle. The typical dosage range for Arimidex is 0.5-1 mg daily; however, this may vary based on individual needs and circumstances. Consult your healthcare provider to determine the optimal dose and timing for you based on your specific situation.
- Can I start Arimidex on cycle?
Arimidex is an aromatase inhibitor commonly used during steroid cycles to prevent testosterone conversion into estrogen. It's typically recommended to start taking Arimidex at the start of your cycle in order to prevent estrogen buildup in your body; however, always consult a healthcare professional before beginning any medication or supplement, including Arimidex.
- Does Arimidex increase muscle mass?
No, Arimidex (anastrozole) does not directly increase muscle mass. It is an aromatase inhibitor commonly used by bodybuilders and athletes to control estrogen levels while taking anabolic steroids. By decreasing estrogen in the body, Arimidex helps prevent side effects related to estrogen such as gynecomastia (breast tissue growth) or water retention. However, this drug does not have a performance-enhancing effect and has no direct impact on muscle growth or strength.
- What's better Arimidex or Nolvadex?
Arimidex (anastrozole) and Nolvadex (tamoxifen) are medications prescribed to treat and prevent breast cancer in women. Bodybuilders take Arimidex to reduce estrogen levels in their systems while Nolvadex blocks estrogen binding receptors. As these drugs work differently and have different uses, it's difficult to say which one is superior without knowing the specific context in which they're being utilized.
- Does Arimidex cause hair loss?
Arimidex (anastrozole) has not been known to commonly cause hair loss; however, this has been reported as a rare side effect in some cases. If you are experiencing hair loss while taking Arimidex, it's recommended that you speak with your healthcare provider.
- Will Arimidex help erectile dysfunction?
Arimidex is not typically prescribed to treat erectile dysfunction, and there is no evidence to support its effectiveness. As an aromatase inhibitor, Arimidex is typically used to treat breast cancer in women and protect men who are on testosterone replacement therapy or using anabolic steroids. While some studies suggest Arimidex may increase testosterone levels in men, it is not typically recommended for this purpose. If you are struggling with erectile dysfunction, speak with your doctor to identify the underlying cause and appropriate treatments.