Disclaimer: The following article is for educational purposes only and does not promote the use of illegal substances. If you have any questions or concerns, Dr. Touliatos is currently available for consultation.
What Is Clenbuterol?
Clenbuterol, a b2-adrenoceptor antagonist and bronchodilator, is used to treat breathing disorders such as:
- Inflammatory Airway Disease (IAD)
- Recurrent Airway Obstruction (RAO)
Clenbuterol has been approved as a prescription medication for humans in several countries since 1977 (although not the US).
What motivates individuals to use Clenbuterol as an Aesthetic?
We have observed clenbuterol to be anabolic in animal research. It increased skeletal muscle mass and reduced fat. This discovery has led to bodybuilders purchasing clenbuterol illicitly and utilizing it in cutting cycles alongside other fat-burning steroids. We have discovered that clenbuterol has a different effect on humans than it does in animals.
Is It Possible for Clenbuterol to Increase Muscle Mass in Humans?
Some users report no anabolic effects from clenbuterol, whereas others report improvements in lean muscle tissue.
According to our observations, clenbuterol may induce anabolism but at a lower level than anabolic androgenic steroids.
Thus, clenbuterol may help bodybuilders retain muscle when cutting, although significant increases in muscle size and strength are uncommon in our experience. It is more an anti-catabolic than anabolic benefit.
Clenbuterol can be taken either orally or as a liquid or an injection.
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What are the benefits of Clenbuterol?
- Fat loss
- Blood flow increases
- Energy efficiency is a key to reducing energy costs.
- Appetite suppression
- Diuretic effects
- No testosterone suppression
1. Fat Loss
Clenbuterol stimulates your central nervous system, increasing the adrenaline and temperature of the body by up to 1 degree.
Consequently, in an attempt to maintain homeostasis, the body stimulates the sweat glands to cool itself back down to its previous temperature.
This constant cooling effect increases total calorie expenditure, thus spiking a user’s basal metabolic rate. Thus, we find users will typically burn more calories at rest than usual.
It is easier for bodybuilders, therefore, to maintain a caloric deficit (due to the elevated metabolism). Clenbuterol also has direct fat-burning effects (similar to other beta-2 agonists) by accelerating the conversion of triglycerides to free fatty acids.
2. Increased Blood Flow
Clenbuterol raises adrenaline levels and shifts the body to fight-or-flight. Consequently, blood flow improves throughout the body as a survival mechanism.
Thus, we have seen clenbuterol improve muscular endurance, enabling bodybuilders to perform more repetitions than usual.
Note : The endurance benefit of clenbuterol is dependent upon the individual and their reaction to it.
Pumps can also become bigger due to superior blood circulation to the muscles.
Stretching the muscle fascia by increasing repetitions and pumping harder may help build new muscles.
Fascia is a connective tissue that surrounds the muscles; however, if excessively tight, muscle growth can be inhibited.
The deep fascia is pushed against by the muscle as it tries to expand. The more flexible the tissue, the higher the potential for hypertrophy. Clenbuterol’s larger pumps will help the fascia become more flexible, reducing friction.
Users also report:
- Recovery after exercise can be accelerated.
- Sleeping less than usual.
Note: When a person remains in fight-or-flight mode for an extended period, cortisol levels can rise excessively, with vasoconstriction occurring. This can cause fatigue and reduce blood flow. It may happen in the later stages of the clenbuterol cycles after the initial increase in flow.
3. Enhanced Energy
Stimulants stimulate the central nervous system. This causes the body to release adrenaline, giving you a burst energy.
Clenbuterol is a powerful stimulant; thus, energy levels will increase notably. After the initial effects wear off, users often experience a crash of low energy, resulting in a dependency on clenbuterol.
The increased intensity of workouts can help (indirectly). For example, users may perform cardiovascular exercise on a stationary bike for 15 minutes; however, on clenbuterol, individuals may be able to extend the duration to 20+ minutes.
4. Appetite Suppression
Clenbuterol has a stimulating effect on beta-2 adrenergic receptors, which can affect satiety levels in humans. Our patients report less hunger during the day despite burning more calorie. This effect can indirectly assist with further fat loss due to users being more likely to eat in a calorie deficit.
Clenbuterol is beneficial for someone who has difficulty adhering to a diet. Users will feel fuller longer on clenbuterol and eat less.
5. Diuretic Effects
Clenbuterol expels extracellular water, resulting in a person looking visibly leaner and having increased muscle tone. Clenbuterol diuretic effect is attributed to sweating.
Therefore, it is important to drink adequate
levels of water when taking clenbuterol, as sodium is lost through sweat, which can lead to dehydration and muscle cramps.
Any water lost from taking clenbuterol is likely to return post-cycle, making this diuretic effect temporary.
6. No Testosterone Suppression
Anabolic steroids can cause the natural production of testosterone to be shut down. Typically, after a steroid cycle, it can take several weeks or months for endogenous testosterone to return to normal levels.
In contrast, clenbuterol does not compromise testosterone levels. Thus, PCT is not required, and results are less likely to be lost post-cycle.
Alternatives to Clenbuterol that are legal
Clenbutrol is our recommended legal clenbuterol product. It mimics the fat-burning and thermogenic effects of clenbuterol, but without any increases in heart rate or blood pressure.
Clenbutrol is an FDA-approved formula and does not require a prescription for purchase.
Clenbutrol can be taken by men or women to significantly decrease their fat mass, while enhancing muscle tone.
What are the side effects of Clenbuterol?
- Heart rate increases
- Anxiety
- Insomnia
1. Increased Heart Rate
Clenbuterol arouses the sympathetic nervous system, potentially causing users’ resting heart rates to become excessively elevated.
Dr. Thomas O’Connor has also anecdotal proof that clenbuterol contributes to heart rates as high as 180 beats per second.
A patient developed chronic atrial fibrillation after clenbuterol usage (2). This is a type of irregular heartbeat that’s caused by permanent scarring in the heart.
Thus, clenbuterol is an especially dangerous drug for anyone with:
- Cardiac problems in the family
- Existing high blood tension
- Existing heart arrhythmia
Clenbuterol may cause deterioration in health for the average person. Thus, its potential toxicity is not limited to those with genetic susceptibilities for cardiac complications.
2. Anxiety
Clenbuterol can cause anxiety due to its tendency of putting a person in fight-or flight mode. A person’s mental health can be negatively affected by excessive arousal in the central nervous system.
A racing heart and palpitations may also trigger anxiety, as users may think they are having a heart attack.
Taking a sedative may help to calm the central nervous system and reduce anxiety levels. However, we have seen this counteract the thermogenic effect of clenbuterol, thus negatively affecting fat loss due to less adrenaline and heat production.
High levels of CNS stimulation are linked to depression due to the subsequent come-down effect. This is due to clenbuterol initially boosting dopamine levels in the brain (3), for them to drop later as a person builds tolerance or comes off the drug.
Tremors are also common when taking clenbuterol due to its greater adrenaline output. In our experience, this side effect is particularly common in the hands.
3. Insomnia
Hyperactivity and an overly active nervous systems can cause insomnia in clenbuterol consumers (4).
Some bodybuilders suggest taking clenbuterol earlier in the day to improve the chances of falling asleep at night. However, clenbuterol has a long half-life of 35 hours (5). We have therefore found that this protocol is ineffective. High levels of clenbuterol are still circulating in the bloodstream.
It is worth noting that sleep deprivation may elevate cortisol levels, further increasing blood pressure and inhibiting fat burning.
Clenbuterol Dosage
A person’s dosage will depend on what they are using clenbuterol for. Asthmatics may take up to two 20-mcg tablets per day. Patients suffering more severely from respiratory issues may take four 20-mcg pills per day.
Bodybuilders and anyone who is taking clenbuterol to lose weight can take up to 6-8 pills per dose (120-160mcg). Such dosages are well beyond the therapeutic range used in medicine; therefore, more severe side effects are to be expected.
People respond to potent stimulants differently; thus, the dosage can also be tailored to how sensitive a person is to the drug.
What are the differences in dosage between men and women?
The dosage for clenbuterol, unlike anabolic steroids is the same in men and women. This is because it affects the CNS rather than working on a hormonal level (where women have significantly less testosterone and thus need smaller doses of steroids to obtain the same level of results).
Men and women can both benefit from the following cycle to improve fat loss and muscle definition.
Users typically develop a tolerance quickly to clenbuterol. To prolong the positive effects of clenbuterol, we recommend that consumers start with a low dosage, and gradually increase it every third day.
Users typically increase their dosage only until they reach maximum. We have had patients complete a 30-day clenbuterol cycle, reaching a peak dose of 120 mcg without significant, short-term complications. However, we have also had patients report severe side effects on 80 mcg/day (and thus have to cut their cycle short).
It is because of beta-receptor deregulation that clenbuterol cycle typically does not last more than 4-6 weeks.
The positive effects of clenbuterol can only last for a short time before the body’s temperature returns to normal. This causes fat burning to stop.
Consequently, some users choose to cycle clenbuterol for 2 weeks on, followed by 2 weeks off, or 2 days on and 2 days off.
2-Week on/off Clenbuterol Cycle
In some cases, as mentioned above, short clenbuterol cycle are used to ensure that the body does not develop a tolerance for the drug and to continue fat loss on future cycles. Furthermore, we have found that a shorter 2-week cycle is less cardiotoxic compared to longer cycles.
One journal reported that a 25-year old man who was healthy, had been rushed to an emergency room after taking 20 mcg
Clenbuterol is a steroid. He was diagnosed with labile hypertension, and his heart rate reached 140 beats per minute.
He experienced:
- Palpitations
- Nausea
- Chest pain
- Sweating
- Anxiety
He had been taking the same dose for the last 3 weeks with no adverse effects. This case shows how a two-week cycle is less harmful for sensitive users.
A 2-week cycle will often start in the 20-40 mcg range, with the dose increasing every 1 or 2 days until a maximum dose is achieved (usually 100 mcg-140 mcg).
Most users will rest for 2 weeks before cycling clenbuterol. However, the second cycle begins with the maximum dose from the first cycle. Thus, if the first cycle finished at 100 mcg per day, the same dose would be taken for the entire 2 weeks in the second cycle.
From this point forward, every subsequent cycle will start at the maximum dosage for continued progress.
Clenbuterol, Winstrol and Winstrol
For Men
Winstrol is an anabolic steroid utilized during cutting cycles to enhance fat loss and lean muscle mass.
The addition of Winstrol will have a more anabolic effect than taking clenbuterol alone. Thus, a person will build muscle and burn fat simultaneously on this stack, rather than predominantly burning fat with clenbuterol.
Winstrol has different side effects than clenbuterol. Winstrol, like clenbuterol, is a compound that is taken orally. However it is very hepatotoxic. Winstrol users often have high ALT/AST levels in our liver function tests, indicating a significant strain on their liver. LDL cholesterol levels will also rise, causing a substantial spike in blood pressure.
Other possible side effects of high DHT levels are:
- Hair loss
- Prostate enlargement
- Acne vulgaris
Winstrol can also cause endogenous testosterone production to shut down, taking several months for levels to recover back to normal (hence why bodybuilders opt for post-cycle therapy).
For Women
Winstrol is generally not a recommended steroid for women, due to the high chances of virilization occurring. Such masculine effects, however, may be reduced by adopting a low dosage (as shown below).
Winstrol may be a deterrent for women who are primarily interested in fat loss. Winstrol is known to compromise femininity. If additional muscle size and tone is required, women may use clenbuterol with Winstrol.
Clenbuterol (T3) and Cytomel Cycle
Clenbuterol can also be stacked with Cytomel (synthetic T3) to enhance fat burning. Cytomel is a prescription medication for hypothyroidism (an underactive thyroid).
In general, the higher the T3 level, the faster the fat is burned in the body. This stack is effective, but not without side effects. These can include:
- Anxiety
- Depression
- Brain fog
- Flushing
- High blood pressure
- Arrhythmias
Cytomel is commonly taken by users for 6-8 weeks at a dosage of 25-75mcg per day.
50 mcg is the standard Cytomel dose for intermediate bodybuilders. However, they may stack Cytomel with testosterone or another anabolic steroid due to T3’s potential catabolic effects.
Clenbuterol (Before and After Pictures).
The user (above) cycled clenbuterol for 2 weeks, starting with a 20 mcg dose and slowly increasing up to 80 mcg/day. This was the first time that this user had used clenbuterol.
We see a person’s results on clenbuterol commonly determined by:
- Dosage
- Cycle length
- Genetics
- Diet
- Workout routines
For enhanced fat loss, users may eat within a 500-calorie deficit. Clenbuterol can have its metabolic effects reduced if you eat more than 500 calories.
According to our experience, both men and women lose between 10-15 pounds after a 4-week cycle using clenbuterol.
Similarly to steroids, the more clenbuterol cycles a person performs, the less fat loss they are likely to experience with each one.
Clenbutrol Reviews: Before and After Pictures
Crazy Bulk formulates Clenbutrol as a legal substitute to clenbuterol.
Balwinder’s results from taking Clenbutrol for 5 weeks.
John Miller’s results after taking Crazy Bulk cutting stack (including Clenbutrol for 8 weeks).
Kim lost 8 pounds in 1 month after taking Clenbutrol Anvarol and Winsol. She lost 2 inches on her waist and 2.5 inches on her hips.
FAQs
Clenbuterol and Albuterol: What’s the difference?
Albuterol sulfate (also referred to as salbutamol) is a beta-2 adrenergic agonist, like clenbuterol.
Albuterol, on the other hand, is a prescription-only drug that is FDA approved and available for treating asthma.
Albuterol stimulates the CNS to burn fat. Albuterol has similar benefits and side-effects to clenbuterol.
However, albuterol is not as potent as clenbuterol, being regarded as a cleaner stimulant.
Consequently, albuterol’s side effects can be more tolerable, potentially making it more cardiovascular-friendly. However, the results on albuterol are less noticeable in our experience, with fat loss and energy levels being more prominent on clenbuterol.
Albuterol has a shorter half life than clenbuterol (4-6 hours), so it is necessary to take more doses.
Albuterol is administered in the same way as clenbuterol, but in pill form. Albuterol, however, is prescribed as an emergency inhaler in medicine.
Is Clenbuterol Legal?
Clenbuterol, which is not included in the Controlled Substances Act, is technically legal for use in the US.
It is not FDA approved, and users should be aware that it can have potentially harmful side effects.
Clenbuterol, too, is on the WADA list of banned substances. Athletes can be disqualified from a drug-test if they are found to have it in their system.
Is Clenbuterol Safe?
The FDA does not approve clenbuterol as a human drug, indicating
its toxic nature.
The Peking Union Medical College in Beijing, China, concluded that clenbuterol only had mild effects when given to rabbits (7). However, when higher doses were administered, their heart rates increased drastically, inducing severe hypotension.
Research suggests that the severity and duration of adverse effects from clenbuterol may depend on dose (8). Anecdotally, we have found high dosages to be unsafe regarding cardiotoxicity.
Note Men and women who have heart problems are at high-risk when taking clenbuterol. If users stack clenbuterol and anabolic steroids together, the cardiac side effects are exacerbated (9).
Is Weight Loss Induced by Clenbuterol Permanent?
If a person continues to consume calories at a deficit or maintenance level, the results of clenbuterol will remain.
However, if a person begins to overeat following a clenbuterol cycle and stops training, then fat accumulation can occur.
Note : The only effect that is inherently temporary is water loss. Users may recover a small amount when they complete their cycle.
Is Clenbuterol Effective?
Clenbuterol, a lipolytic drug, is effective.
It is hard to tell if clenbuterol purchased at the counter is authentic.
Generally, if users are not experiencing fat loss or their body temperature is not rising, it is unlikely to be clenbuterol.
Is It Permissible for Users to Consume Alcohol While Taking Clenbuterol?
Alcohol consumption is usually a detrimental idea when taking oral anabolic steroids due to their hepatotoxic nature. Clenbuterol, however, is not anabolic, but a bronchodilator and is not toxic to liver.
The main concerns we see with clenbuterol are excessive rises in heart rate, blood pressure fluctuations, and dehydration. We advise against alcohol because it will increase all three side effects.
Alcohol will also blunt the fat burning effects of clenbuterol. This is especially true in stubborn areas due to cortisol, a hormone that stores fat.
Clenbuterol Pros and Cons
Pros:
- Fat loss is significant
- Effective bronchodilator
- Anti-catabolic Effects
Cons:
- Increased risk of tachycardia
- Excess stimulation of the central nervous system.
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